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加拉帕戈斯暂停入组GLPG 5301的1/2期研究

2024-08-03 03:05

  • Galapagos (NASDAQ:GLPG) said it has paused enrollment in a Phase 1/2 study of its therapy candidate GLPG5301 after a case of Parkinsonism was observed. 
  • The Belgium-based biotech company said in its earnings release late Thursday that it has temporarily halted enrollment in the study, called PAPILIO-1, and submitted a protocol amendment to the European Medicines Agency. 
  • According to the National Institutes of Health, Parkinsonism is a “broad term referring to various neurodegenerative diseases that manifest with motor symptoms such as rigidity, tremors, and bradykinesia.”
  • Galapagos (GLPG) has been evaluating GLPG5301, a CAR-T therapy, as a potential treatment for relapsed/refractory multiple myeloma, according to its website.
  • The company added that it expects to resume recruitment for the study “in the coming months.”

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