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Janux治疗公司宣布PSMA-TRACTr JANX007 1a阶段剂量升级的中期临床数据和流水线计划的最新情况
2023-07-17 20:02
- Multiple patients treated with PSMA-TRACTr JANX007 have achieved meaningful PSA drops coupled with manageable safety and CRS
- PSMA-TRACTr JANX007 and EGFR-TRACTr JANX008 have been generally well tolerated at levels above the projected maximum tolerable dose of the parental T cell engagers
- JANX007 preliminary data showed encouraging safety results consistent with on-tumor activity with no dose-limiting toxicities
- PK exposure demonstrated TRACTr activation with lack of TCE accumulation
- No treatment-emergent ADA titers observed
- Janux to host virtual investor event today at 4:00 PM Eastern Time
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