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Vertex为糖尿病候选人授权细胞治疗技术

2024-04-23 21:12

  • Vertex Pharmaceuticals (NASDAQ:VRTX) announced Tuesday an agreement with French biotech TreeFrog Therapeutics to obtain an exclusive license for the latter’s cell manufacturing technology, C-Stem, targeting VRTX’s cell therapies for type 1 diabetes.
  • Under the collaboration, the duo will scale up the development of differentiated, insulin-producing pancreatic islet cells with a focus on VRTX’s T1D cell therapy portfolio.
  • As part of the agreement, TreeFrog will receive $25M upfront and an equity investment from Vertex (VRTX), a U.S. biotech focused on cystic fibrosis therapies. It’s also eligible to receive up to $215M in milestone payments in connection with an initial development process.
  • Payments linked to clinical, regulatory, and commercial milestones for two potential products are expected to reach $250M in addition to single-digit royalties.

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