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帕金森治疗早期数据公布后收益下滑

2024-08-29 20:33

  • Gain Therapeutics (NASDAQ:GANXfell ~12% premarket Thursday after the biotech posted initial data from a Phase 1 trial for its lead asset GT-02287 targeted at Parkinson’s disease.
  • According to Gain (GANX), the study of 72 healthy volunteers indicated that single and multiple doses of GT-02287, including the highest planned dose levels, were safe and generally well tolerated across all age groups. The experimental therapy was found to be present in cerebrospinal fluid with peripheral target engagement.
  • The company announced plans to begin a trial for GT-02287 in Parkinson’s disease patients by Q4 2024 and generate its data by mid-2025.
  • “We are enthusiastic about the promising profile of GT-02287, particularly with the added observation of CNS exposure and target engagement,” interim CEO Gene Mack remarked.

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